In this text we reviewed tree cases of osteopetrosis. First patient, a boy, 17 years of age, had a long history of moderately severe artralgias. His physical examination was normal with the exception of slight lumbalgia during lumbar extention. The second patient was a young man aged 35 years old. He complained of graduatiy increasing pain and numbness in the lumbar column, approximately 7 years duration. The trirth one was an old man aged 70 years old. He had some skeletal complaints, The roentgenograms of the patients revealed increased density of pelvis and femoral and of the vertebral column, but there were neither fracture nor anemia. Albers-Schönberg (also= known as osteopetrosis, osteoscierosis, marbie bones etc.) disease is an hereditary disorder that is believed to be transmitted as a mendelian recessive. Here, the principal character is sclerosis of bone with resuitant marked thickenning of the bony cortex and narowing or even filling of the marow cavity. As mentioned before, primary defect in this disease is failure of absorption of primary spongiosa in the process of enchondral bone formation.
Özet
Yazımızda bel ağrısından şikayetle polikliniğimize müracaat eden üç hastada tesbit ettiğimiz osteopetrosis incelendi. Nadir görülen genotipik hastalıklardan biri olan osteopetrosis (Albers Schönberg hastalığı) hakkında klinik, radyolojik, laboratuar bulgularla ayırıcı teşhis yönünden literatür taranarak takdim edildi.
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